{"product_id":"mebhydroline-e4873","title":"Mebhydroline","description":"\u003cp\u003e\u003cstrong\u003eMebhydroline\u003c\/strong\u003e is an antagonist of FXR used in studies of PI3K-Akt-mTOR Signaling and Hormone Signaling and related signaling programs. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs and ligand-dependent transcriptional programs and endocrine regulation in endocrinology, metabolism, and neuroscience models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking FXR, Mebhydroline can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology, metabolism, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving FXR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Hormone Signaling and related signaling programs\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Mebhydroline is appropriate when a defined chemical perturbant is needed to connect FXR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology, metabolism, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804971868505,"sku":"E4873-5MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804971901273,"sku":"E4873-25MG","price":488.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804971934041,"sku":"E4873-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57804971966809,"sku":"E4873-1G","price":2918.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E4873-Mebhydroline-chemical-structure.png?v=1776170225","url":"https:\/\/absource.de\/products\/mebhydroline-e4873","provider":"Absource Diagnostics","version":"1.0","type":"link"}