{"product_id":"melk-8a-dihydrochloride-s0430","title":"MELK-8a Dihydrochloride","description":"\u003cp\u003e\u003cstrong\u003eMELK-8a Dihydrochloride\u003c\/strong\u003e is an inhibitor linked to PI3K-Akt-mTOR Signaling and related pathway-oriented research. It is especially relevant in biochemical and cell-based models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs.\u003c\/p\u003e\n\n\u003cp\u003eThe pathway annotation connects MELK-8a Dihydrochloride to PI3K-Akt-mTOR Signaling, supporting experiments that monitor growth-factor signaling, survival control, and nutrient-sensing outputs across biochemical, cellular, or phenotypic assay formats. This context is compatible with AKT\/mTOR readouts, pathway-response, and viability assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. When a fully resolved mechanism is unavailable, parallel readouts such as viability, reporter activity, morphology, localization, or biochemical conversion can still help position the compound experimentally.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003cli\u003eMechanism-oriented follow-up using biochemical and cellular endpoints\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, MELK-8a Dihydrochloride is well suited to pathway-oriented studies that need a defined compound input for PI3K-Akt-mTOR Signaling readouts in biochemical and cell-based models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 5 mg","offer_id":57805115162969,"sku":"S0430-5MG","price":586.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 25 mg","offer_id":57805115195737,"sku":"S0430-25MG","price":1444.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 100 mg","offer_id":57805115228505,"sku":"S0430-100MG","price":2938.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 5 mg","offer_id":58478345126233,"sku":"C07175-5MG","price":437.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 25 mg","offer_id":58478345159001,"sku":"C07175-25MG","price":1079.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 100 mg","offer_id":58478345191769,"sku":"C07175-100MG","price":2195.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s0430-melk-8a-dihydrochloride-chemical-structure.gif?v=1776172177","url":"https:\/\/absource.de\/products\/melk-8a-dihydrochloride-s0430","provider":"Absource Diagnostics","version":"1.0","type":"link"}