{"product_id":"mirin-s8096","title":"Mirin","description":"\u003cp\u003e\u003cstrong\u003eMirin\u003c\/strong\u003e is an inhibitor of ATM and ATR used in studies of DNA Damage Response. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control in cancer, cell signaling, and dna damage \/ repair models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting ATM and ATR, Mirin can be used to examine checkpoint activation, DNA repair, and genome-stability control. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving ATM and ATR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Mirin is appropriate when a defined chemical perturbant is needed to connect ATM and ATR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57809577476441,"sku":"S8096-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57809577509209,"sku":"S8096-50MG","price":291.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809577541977,"sku":"S8096-1G","price":1955.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809577574745,"sku":"S8096-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/mirin-chemical-structure-s8096.gif?v=1776202301","url":"https:\/\/absource.de\/products\/mirin-s8096","provider":"Absource Diagnostics","version":"1.0","type":"link"}