{"product_id":"mito-lnd-mito-lonidamine-e5927","title":"Mito-LND (Mito-Lonidamine)","description":"\u003cp\u003e\u003cstrong\u003eMito-LND (Mito-Lonidamine)\u003c\/strong\u003e is an inhibitor of OXPHOS used in studies of PI3K-Akt-mTOR Signaling and Oxidative Stress Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to growth-factor signaling, survival control, and nutrient-sensing outputs and redox signaling, ROS handling, and antioxidant defenses in metabolism and oxidative stress models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting OXPHOS, Mito-LND (Mito-Lonidamine) can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and redox signaling, ROS handling, and antioxidant defenses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In metabolism and oxidative stress models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving OXPHOS\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Oxidative Stress Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Mito-LND (Mito-Lonidamine) is appropriate when a defined chemical perturbant is needed to connect OXPHOS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in metabolism and oxidative stress models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805003522393,"sku":"E5927-5MG","price":194.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805003555161,"sku":"E5927-25MG","price":488.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57805003587929,"sku":"E5927-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805003620697,"sku":"E5927-1G","price":2919.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E5927-chemical-structure.png?v=1776170570","url":"https:\/\/absource.de\/products\/mito-lnd-mito-lonidamine-e5927","provider":"Absource Diagnostics","version":"1.0","type":"link"}