{"product_id":"mks3-nphp11-or-meckelin-or-tmem67-xenopus-antibody-ffpe-validated","title":"MKS3 (NPHP11 or Meckelin or TMEM67) (Xenopus) Antibody - FFPE Validated","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\n\u003cp\u003eUse this antibody to examine MKS3 (NPHP11) in your model system. MKS3 is a trafficking-related component that can localize to basal bodies and ciliary axonemes. Look for shifts in distribution that track with phenotype changes.\u003c\/p\u003e\n\u003cp\u003eTracking MKS3 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.\u003c\/p\u003e\n\u003ch2\u003eResearch Context\u003c\/h2\u003e\n\u003cp\u003eDisruption of intraflagellar transport or basal body function can produce distinct localization signatures. Pair measurements with orthogonal readouts when interpretation is sensitive to context.\u003c\/p\u003e\n\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003esignal enrichment at basal bodies versus cytoplasm\u003c\/li\u003e\n\u003cli\u003echanges in cilia incidence or apparent length in perturbation studies\u003c\/li\u003e\n\u003cli\u003ecell-cycle linked differences in localization\u003c\/li\u003e\n\u003cli\u003eco-occurrence with intraflagellar transport markers\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\n\u003cp\u003eThis fixed-section oriented version is intended for paraffin-embedded tissue, where crosslinking and retrieval steps can shape epitope accessibility. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.\u003c\/p\u003e\n\u003cp\u003eTo support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so MKS3 patterns can be compared across experiments without guesswork.\u003c\/p\u003e\n\u003cp\u003eTo support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so MKS3 patterns can be compared across experiments without guesswork.\u003c\/p\u003e\n\u003cp\u003eWith a clear focus on MKS3 (NPHP11), this fixed-section option fits streamlined studies and fast iteration.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101372223833,"sku":"90103X-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101372256601,"sku":"90103X-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101372289369,"sku":"90103X-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101372322137,"sku":"90103X-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101372354905,"sku":"90103X-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101372387673,"sku":"90103X-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/mks-xenopus_e7dc3a20-76b7-40d7-aa0d-83ee1070b54f.jpg?v=1779279417","url":"https:\/\/absource.de\/products\/mks3-nphp11-or-meckelin-or-tmem67-xenopus-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}