{"product_id":"ml385-s8790","title":"ML385","description":"\u003cp\u003e\u003cstrong\u003eML385\u003c\/strong\u003e is an inhibitor of NRF2 used in studies of Oxidative Stress Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to redox signaling, ROS handling, and antioxidant defenses in immunology, inflammation, and metabolism models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting NRF2, ML385 can be used to examine redox signaling, ROS handling, and antioxidant defenses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In immunology, inflammation, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving NRF2\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Oxidative Stress Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, ML385 is appropriate when a defined chemical perturbant is needed to connect NRF2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology, inflammation, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809650254169,"sku":"S8790-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809650286937,"sku":"S8790-25MG","price":461.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809650319705,"sku":"S8790-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809650352473,"sku":"S8790-1G","price":1641.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809650385241,"sku":"S8790-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/ml385-chemical-structure-s8790.gif?v=1776204758","url":"https:\/\/absource.de\/products\/ml385-s8790","provider":"Absource Diagnostics","version":"1.0","type":"link"}