{"product_id":"mli-2-s9694","title":"MLi-2","description":"\u003cp\u003e\u003cstrong\u003eMLi-2\u003c\/strong\u003e is an inhibitor of LRRK2 used in studies of Autophagy. In practice, this places the compound in experiments that measure autophagic flux, lysosomal turnover, and stress adaptation in autophagy, cancer, and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting LRRK2, MLi-2 can be used to examine autophagic flux, lysosomal turnover, and stress adaptation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving LRRK2\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Autophagy\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, MLi-2 is appropriate when a defined chemical perturbant is needed to connect LRRK2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809740038489,"sku":"S9694-5MG","price":213.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809740071257,"sku":"S9694-25MG","price":645.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809740104025,"sku":"S9694-1ML\/DMSO","price":265.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s9694-mli-2-chemical-structure.gif?v=1776205210","url":"https:\/\/absource.de\/products\/mli-2-s9694","provider":"Absource Diagnostics","version":"1.0","type":"link"}