{"product_id":"mme-antibody-sc-f3024","title":"CD10\/Neprilysin Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eMME is a target of interest in many antibody-based workflows. CD10\/Neprilysin , also known as neutral endopeptidase (NEP), is a zinc-dependent type II transmembrane metalloprotease with its catalytic domain exposed extracellularly, enabling the degradation of a wide range of bioactive peptides. Structurally, it consists of an intracellular domain, a single transmembrane region, and a large extracellular domain responsible for zinc binding and enzymatic activity. Depending on the literature source, MME may also be discussed as CD10\/Neprilysin and Atriopeptidase Common acute lymphocytic leukemia antigen (CALLA).\u003c\/p\u003e\u003cp\u003eReported cellular context includes cellmembrane and membrane, which can matter when signal is compared across treatments or changing cell states. Following MME across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eMME is commonly interpreted in the context of immunology and neuroscience research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cellmembrane and membrane, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cellmembrane and membrane across matched conditions\u003c\/li\u003e\n\u003cli\u003econtext differences tied to immune-cell state, activation, or lineage composition\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for MME. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in MME reflect biology rather than handling. When interpreting MME, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep MME trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 20 µl","offer_id":57577999728985,"sku":"F3024-20UL","price":159.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 100 µl","offer_id":57577999761753,"sku":"F3024-100UL","price":339.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 2 × 100 µl","offer_id":57577999794521,"sku":"F3024-2X100UL","price":499.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 20 µl","offer_id":58477404094809,"sku":"C06503-20UL","price":126.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 100 µl","offer_id":58477404127577,"sku":"C06503-100UL","price":284.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F3024-IF.png?v=1773600895","url":"https:\/\/absource.de\/products\/mme-antibody-sc-f3024","provider":"Absource Diagnostics","version":"1.0","type":"link"}