{"product_id":"mnng-1-methyl-3-nitro-1-nitrosoguanidine-e0157","title":"MNNG (1-Methyl-3-nitro-1-nitrosoguanidine)","description":"\u003cp\u003e\u003cstrong\u003eMNNG (1-Methyl-3-nitro-1-nitrosoguanidine)\u003c\/strong\u003e is an inhibitor linked to DNA Damage Response and related pathway-oriented research. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control in cancer and dna damage \/ repair models.\u003c\/p\u003e\n\n\u003cp\u003eThe pathway annotation connects MNNG (1-Methyl-3-nitro-1-nitrosoguanidine) to DNA Damage Response, supporting experiments that monitor checkpoint activation, DNA repair, and genome-stability control across biochemical, cellular, or phenotypic assay formats. This context is compatible with DNA-repair, checkpoint, and genotoxic-stress assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cancer and dna damage \/ repair models\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, MNNG (1-Methyl-3-nitro-1-nitrosoguanidine) is well suited to pathway-oriented studies that need a defined compound input for DNA Damage Response readouts in cancer and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"100 mg","offer_id":57804220039513,"sku":"E0157-100MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57804220072281,"sku":"E0157-1G","price":291.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e0157-n-methyl-n-nitro-nitrosoguanidine-chemical-structure.gif?v=1776165787","url":"https:\/\/absource.de\/products\/mnng-1-methyl-3-nitro-1-nitrosoguanidine-e0157","provider":"Absource Diagnostics","version":"1.0","type":"link"}