{"product_id":"msx-127-s0292","title":"MSX-127","description":"\u003cp\u003e\u003cstrong\u003eMSX-127\u003c\/strong\u003e is an antagonist of CXCR used in studies of Immune Signaling and GPCR Signaling. It is especially relevant in immunology and inflammation models, where defined compound exposure can be linked to cytokine-mediated signaling and inflammatory effector responses and receptor-driven second-messenger signaling and desensitization dynamics.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking CXCR, MSX-127 can be used to examine cytokine-mediated signaling and inflammatory effector responses and receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving CXCR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Immune Signaling and GPCR Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, MSX-127 is appropriate when a defined chemical perturbant is needed to connect CXCR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805094060377,"sku":"S0292-5MG","price":301.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805094093145,"sku":"S0292-25MG","price":913.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s0292-msx-127-chemical-structure.gif?v=1776172034","url":"https:\/\/absource.de\/products\/msx-127-s0292","provider":"Absource Diagnostics","version":"1.0","type":"link"}