{"product_id":"mtco1-antibody-sc-f1628","title":"MTCO1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eMTCO1 is a target of interest in many antibody-based workflows. Mitochondrial cytochrome c oxidase 1 (MT-CO1) is a key member of the cytochrome c family involved in cellular energy production and apoptosis. It is the main catalytic subunit of complex IV in the mitochondrial respiratory chain, encoded by mitochondrial DNA alongside MT-CO2 and MT-CO3, while other subunits encoded by nuclear DNA protect the catalytic core.\u003c\/p\u003e\u003cp\u003eReported cellular context includes mitochondrion inner membrane, which can matter when signal is compared across treatments or changing cell states. Following MTCO1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eMTCO1 is commonly interpreted in the context of metabolism and apoptosis research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans mitochondrion inner membrane, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003esignal enrichment within mitochondrion inner membrane relative to the broader cellular background\u003c\/li\u003e\n\u003cli\u003eresponses linked to nutrient status, mitochondrial state, or metabolic rewiring\u003c\/li\u003e\n\u003cli\u003eseparation of survival-associated changes from stress or death-associated readouts\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for MTCO1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in MTCO1 reflect biology rather than handling. When interpreting MTCO1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep MTCO1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577800401241,"sku":"F1628-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577800434009,"sku":"F1628-100UL","price":329.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577800466777,"sku":"F1628-2X100UL","price":489.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1628-IHC1.jpg?v=1773599959","url":"https:\/\/absource.de\/products\/mtco1-antibody-sc-f1628","provider":"Absource Diagnostics","version":"1.0","type":"link"}