{"product_id":"nerandomilast-bi-1015550-e1382","title":"Nerandomilast (BI 1015550)","description":"\u003cp\u003e\u003cstrong\u003eNerandomilast (BI 1015550)\u003c\/strong\u003e is an inhibitor of PDE used in studies of enzyme regulation. It is especially relevant in cardiovascular, immunology, and inflammation models, where defined compound exposure can be linked to catalytic activity, substrate turnover, and enzymatic regulation.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting PDE, Nerandomilast (BI 1015550) can be used to examine catalytic activity, substrate turnover, and enzymatic regulation. This target class is commonly examined through enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping. In cardiovascular, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PDE\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cardiovascular, immunology, and inflammation models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Nerandomilast (BI 1015550) is appropriate when a defined chemical perturbant is needed to connect PDE with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804389876057,"sku":"E1382-5MG","price":167.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804389908825,"sku":"E1382-25MG","price":500.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1382-bi-1015550-chemical-structure.png?v=1776166847","url":"https:\/\/absource.de\/products\/nerandomilast-bi-1015550-e1382","provider":"Absource Diagnostics","version":"1.0","type":"link"}