{"product_id":"nh125-s7436","title":"NH125","description":"\u003cp\u003e\u003cstrong\u003eNH125\u003c\/strong\u003e is an inhibitor of PKA and PKC used in studies of MAPK \/ ERK Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in cancer, cell signaling, and neuroscience models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting PKA and PKC, NH125 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PKA and PKC\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to MAPK \/ ERK Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, NH125 is appropriate when a defined chemical perturbant is needed to connect PKA and PKC with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"2 mg","offer_id":57809484022105,"sku":"S7436-2MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809484054873,"sku":"S7436-25MG","price":586.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/NH125-chemical-structure-s7436.gif?v=1776201377","url":"https:\/\/absource.de\/products\/nh125-s7436","provider":"Absource Diagnostics","version":"1.0","type":"link"}