{"product_id":"nicur-e0068","title":"NiCur","description":"\u003cp\u003e\u003cstrong\u003eNiCur\u003c\/strong\u003e is an inhibitor of Histone Acetyltransferases used in studies of Apoptosis and Epigenetic Regulation. In practice, this places the compound in experiments that measure caspase-associated cell-death signaling and survival decisions and chromatin-state control, histone modification, and transcriptional regulation in cancer and epigenetics models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Histone Acetyltransferases, NiCur can be used to examine caspase-associated cell-death signaling and survival decisions and chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Histone Acetyltransferases\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Apoptosis and Epigenetic Regulation\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eChromatin, epigenetic, and gene-expression profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, NiCur is appropriate when a defined chemical perturbant is needed to connect Histone Acetyltransferases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804192022873,"sku":"E0068-5MG","price":183.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e0068-nicur-chemical-structure.gif?v=1776165643","url":"https:\/\/absource.de\/products\/nicur-e0068","provider":"Absource Diagnostics","version":"1.0","type":"link"}