{"product_id":"nidufexor-lmb-763-s0037","title":"Nidufexor (LMB-763)","description":"\u003cp\u003e\u003cstrong\u003eNidufexor (LMB-763)\u003c\/strong\u003e is an agonist of FXR used in studies of Hormone Signaling and Metabolic Signaling. In practice, this places the compound in experiments that measure ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology and metabolism models.\u003c\/p\u003e\n\n\u003cp\u003eBy activating FXR, Nidufexor (LMB-763) can be used to examine ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving FXR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Hormone Signaling and Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eAgonist-response and downstream signaling studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Nidufexor (LMB-763) is appropriate when a defined chemical perturbant is needed to connect FXR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805072466265,"sku":"S0037-5MG","price":154.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805072499033,"sku":"S0037-25MG","price":461.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s0037-nidufexor-lmb-763--chemical-structure.gif?v=1776171734","url":"https:\/\/absource.de\/products\/nidufexor-lmb-763-s0037","provider":"Absource Diagnostics","version":"1.0","type":"link"}