{"product_id":"nimbolide-e0455","title":"Nimbolide","description":"\u003cp\u003e\u003cstrong\u003eNimbolide\u003c\/strong\u003e is an inhibitor linked to NF-kB Signaling and Immune Signaling and related signaling programs and related pathway-oriented research. In practice, this places the compound in experiments that measure inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in apoptosis, cancer, and cell cycle models.\u003c\/p\u003e\n\n\u003cp\u003eThe pathway annotation connects Nimbolide to NF-kB Signaling and Immune Signaling and related signaling programs, supporting experiments that monitor inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses across biochemical, cellular, or phenotypic assay formats. This context is compatible with NF-kB reporter, cytokine, and inflammation assays and immune activation, cytokine-response, and mediator-profiling assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePathway perturbation studies connected to NF-kB Signaling and Immune Signaling and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in apoptosis, cancer, and cell cycle models\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Nimbolide is well suited to pathway-oriented studies that need a defined compound input for NF-kB Signaling and Immune Signaling and related signaling programs readouts in apoptosis, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"1 mg","offer_id":57804256575833,"sku":"E0455-1MG","price":441.0,"currency_code":"EUR","in_stock":true},{"title":"5 mg","offer_id":57804256608601,"sku":"E0455-5MG","price":1323.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E0455-Nimbolide-chemical-structure.png?v=1776166051","url":"https:\/\/absource.de\/products\/nimbolide-e0455","provider":"Absource Diagnostics","version":"1.0","type":"link"}