{"product_id":"notch2-antibody-ffpe-validated","title":"NOTCH2 Antibody - FFPE Validated","description":"\u003ch2\u003eProtein Function\u003c\/h2\u003e\n\u003cp\u003eWhen control selection matters, this antibody helps you assess NOTCH2 in a structured study. NOTCH2 is a signaling protein that can relay information through phosphorylation and complex assembly. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.\u003c\/p\u003e\n\u003cp\u003eFollowing NOTCH2 across perturbations can help separate expression effects from compartment shifts.\u003c\/p\u003e\n\u003ch2\u003eExperimental Applications\u003c\/h2\u003e\n\u003cp\u003eWhen comparing conditions, consistent sample handling and normalization are key for meaningful contrasts. Time course design can be decisive when regulation is transient or compartment dependent.\u003c\/p\u003e\n\u003cp\u003eMany workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies. Developmental projects may follow this target across stage-dependent remodeling and tissue patterning.\u003c\/p\u003e\n\u003cp\u003eCommon experimental questions that benefit from target tracking include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003etime-resolved changes following stimulation or inhibition\u003c\/li\u003e\n\u003cli\u003einteraction patterns within multi-protein complexes\u003c\/li\u003e\n\u003cli\u003elocalization shifts between cytoplasm, membrane, and nucleus\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWorkflow Perspective\u003c\/h2\u003e\n\u003cp\u003eThis fixed-section oriented version is intended for paraffin-embedded tissue, where crosslinking and retrieval steps can shape epitope accessibility. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Predefine acceptance criteria for controls before collecting the full dataset.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing NOTCH2 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eThe fixed-section format fits designs where NOTCH2 is evaluated with deliberate controls and careful comparisons.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101551890777,"sku":"51502-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101551923545,"sku":"51502-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101551956313,"sku":"51502-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101551989081,"sku":"51502-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101552021849,"sku":"51502-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101552054617,"sku":"51502-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/not2-e15-skin_44def15f-7dec-4abb-af88-9e760005dec9.jpg?v=1779280348","url":"https:\/\/absource.de\/products\/notch2-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}