{"product_id":"nr1d1-nr1d2-rvr-antibody-sc-f1203","title":"NR1D1 + NR1D2 \/ RVR Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eNR1D1 + NR1D2 \/ RVR is a target of interest in many antibody-based workflows. Nuclear receptor subfamily 1 group D member 1 (NR1D1), also known as REV-ERBα, is a type of intracellular transcription factor and a member of the nuclear receptor family. It is responsible for consolidating circadian oscillators. NR1D1 expression reduces the production and release of IL-6 by binding to the IL-6 promoter region or NF-κB binding motif. Depending on the literature source, NR1D1 + NR1D2 \/ RVR may also be discussed as NR1D1 + NR1D2 \/ RVR.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell projection, cytoplasm, nucleus, and synapse, which can matter when signal is compared across treatments or changing cell states. Following NR1D1 + NR1D2 \/ RVR across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eNR1D1 + NR1D2 \/ RVR is commonly interpreted in the context of neuroscience, inflammation, and developmental biology research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell projection, cytoplasm, and nucleus, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell projection, cytoplasm, and nucleus across matched conditions\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003eresponses associated with cytokine exposure, inflammatory tone, or tissue stress\u003c\/li\u003e\n\u003cli\u003estage-dependent patterns during differentiation, morphogenesis, or lineage commitment\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for NR1D1 + NR1D2 \/ RVR. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in NR1D1 + NR1D2 \/ RVR reflect biology rather than handling. When interpreting NR1D1 + NR1D2 \/ RVR, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep NR1D1 + NR1D2 \/ RVR trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577649668441,"sku":"F1203-20UL","price":199.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577649701209,"sku":"F1203-100UL","price":489.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577649733977,"sku":"F1203-2X100UL","price":729.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1203-IF.png?v=1773599429","url":"https:\/\/absource.de\/products\/nr1d1-nr1d2-rvr-antibody-sc-f1203","provider":"Absource Diagnostics","version":"1.0","type":"link"}