{"product_id":"nsc-185058-s6716","title":"NSC 185058","description":"\u003cp\u003e\u003cstrong\u003eNSC 185058\u003c\/strong\u003e is an inhibitor of Autophagy used in studies of PI3K-Akt-mTOR Signaling and Autophagy. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to growth-factor signaling, survival control, and nutrient-sensing outputs and autophagic flux, lysosomal turnover, and stress adaptation in autophagy and metabolism models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Autophagy, NSC 185058 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and autophagic flux, lysosomal turnover, and stress adaptation. The autophagy modulator annotation adds relevance to autophagy-flux and lysosomal-response studies, together with downstream-response mapping in the same experimental setting. In autophagy and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Autophagy\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Autophagy\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eAutophagy-flux and lysosomal-response studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, NSC 185058 is appropriate when a defined chemical perturbant is needed to connect Autophagy with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"2 mg","offer_id":57809415405913,"sku":"S6716-2MG","price":291.0,"currency_code":"EUR","in_stock":true},{"title":"5 mg","offer_id":57809415438681,"sku":"S6716-5MG","price":579.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/nsc-185058-chemical-structure-s6716.gif?v=1776200343","url":"https:\/\/absource.de\/products\/nsc-185058-s6716","provider":"Absource Diagnostics","version":"1.0","type":"link"}