{"product_id":"oc000459-s2822","title":"OC000459","description":"\u003cp\u003e\u003cstrong\u003eOC000459\u003c\/strong\u003e is an antagonist of GPR used in studies of GPCR Signaling. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics in cell signaling and endocrinology models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking GPR, OC000459 can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cell signaling and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving GPR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to GPCR Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, OC000459 is appropriate when a defined chemical perturbant is needed to connect GPR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805785760089,"sku":"S2822-5MG","price":265.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/OC000459-chemical-structure-s2822.gif?v=1776175777","url":"https:\/\/absource.de\/products\/oc000459-s2822","provider":"Absource Diagnostics","version":"1.0","type":"link"}