{"product_id":"olomorasib-e5847","title":"olomorasib","description":"\u003cp\u003e\u003cstrong\u003eolomorasib\u003c\/strong\u003e is an inhibitor of KRAS used in studies of MAPK \/ ERK Signaling and GPCR Signaling. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and receptor-driven second-messenger signaling and desensitization dynamics in cancer and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting KRAS, olomorasib can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and receptor-driven second-messenger signaling and desensitization dynamics. This context is compatible with phosphorylation mapping, pathway-response, and growth assays and ligand-response, cAMP, calcium-flux, and receptor-pharmacology assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving KRAS\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to MAPK \/ ERK Signaling and GPCR Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cancer and cell signaling models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, olomorasib is appropriate when a defined chemical perturbant is needed to connect KRAS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"1 mg","offer_id":57804996510041,"sku":"E5847-1MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"5 mg","offer_id":57804996542809,"sku":"E5847-5MG","price":341.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804996575577,"sku":"E5847-25MG","price":763.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804996608345,"sku":"E5847-100MG","price":1739.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E5847-olomorasib-chemical-structure.png?v=1776170483","url":"https:\/\/absource.de\/products\/olomorasib-e5847","provider":"Absource Diagnostics","version":"1.0","type":"link"}