{"product_id":"osu-03012-ar-12-s1106","title":"OSU-03012 (AR-12)","description":"\u003cp\u003e\u003cstrong\u003eOSU-03012 (AR-12)\u003c\/strong\u003e is an inhibitor linked to PI3K-Akt-mTOR Signaling and related pathway-oriented research. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs in biochemical and cell-based models.\u003c\/p\u003e\n\n\u003cp\u003eThe pathway annotation connects OSU-03012 (AR-12) to PI3K-Akt-mTOR Signaling, supporting experiments that monitor growth-factor signaling, survival control, and nutrient-sensing outputs across biochemical, cellular, or phenotypic assay formats. This context is compatible with AKT\/mTOR readouts, pathway-response, and viability assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. When a fully resolved mechanism is unavailable, parallel readouts such as viability, reporter activity, morphology, localization, or biochemical conversion can still help position the compound experimentally.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003cli\u003eMechanism-oriented follow-up using biochemical and cellular endpoints\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, OSU-03012 (AR-12) is well suited to pathway-oriented studies that need a defined compound input for PI3K-Akt-mTOR Signaling readouts in biochemical and cell-based models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805221855577,"sku":"S1106-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805221888345,"sku":"S1106-25MG","price":363.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805221921113,"sku":"S1106-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/OSU-03012-chemical-structure-S1106.gif?v=1776172919","url":"https:\/\/absource.de\/products\/osu-03012-ar-12-s1106","provider":"Absource Diagnostics","version":"1.0","type":"link"}