{"product_id":"paeoniflorin-nsc-178886-s2410","title":"Paeoniflorin (NSC 178886)","description":"\u003cp\u003e\u003cstrong\u003ePaeoniflorin (NSC 178886)\u003c\/strong\u003e is an inhibitor of COX used in studies of PI3K-Akt-mTOR Signaling and NF-kB Signaling and related signaling programs. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs and inflammatory transcriptional control and stress-responsive survival signaling in immunology and inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting COX, Paeoniflorin (NSC 178886) can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and inflammatory transcriptional control and stress-responsive survival signaling. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving COX\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and NF-kB Signaling and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Paeoniflorin (NSC 178886) is appropriate when a defined chemical perturbant is needed to connect COX with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"25 mg","offer_id":57805604127065,"sku":"S2410-25MG","price":108.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805604159833,"sku":"S2410-1G","price":953.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Paeoniflorin-chemical-structure-s2410.gif?v=1776175003","url":"https:\/\/absource.de\/products\/paeoniflorin-nsc-178886-s2410","provider":"Absource Diagnostics","version":"1.0","type":"link"}