{"product_id":"parsaclisib-incb050465-e0121","title":"Parsaclisib (INCB050465)","description":"\u003cp\u003e\u003cstrong\u003eParsaclisib (INCB050465)\u003c\/strong\u003e is an inhibitor of PI3K delta used in studies of PI3K-Akt-mTOR Signaling. It is especially relevant in cancer, cell signaling, and immunology models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting PI3K delta, Parsaclisib (INCB050465) can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PI3K delta\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Parsaclisib (INCB050465) is appropriate when a defined chemical perturbant is needed to connect PI3K delta with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804207882585,"sku":"E0121-5MG","price":579.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804207915353,"sku":"E0121-25MG","price":1739.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e0121-parsaclisib-chemical-structure.gif?v=1776165716","url":"https:\/\/absource.de\/products\/parsaclisib-incb050465-e0121","provider":"Absource Diagnostics","version":"1.0","type":"link"}