{"product_id":"pdm-11-s0155","title":"PDM-11","description":"\u003cp\u003e\u003cstrong\u003ePDM-11\u003c\/strong\u003e is an antagonist of Estrogen Receptor used in studies of Hormone Signaling. It is especially relevant in cancer, endocrinology, and metabolism models, where defined compound exposure can be linked to ligand-dependent transcriptional programs and endocrine regulation.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking Estrogen Receptor, PDM-11 can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cancer, endocrinology, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Estrogen Receptor\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Hormone Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, PDM-11 is appropriate when a defined chemical perturbant is needed to connect Estrogen Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, endocrinology, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805083935065,"sku":"S0155-5MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805083967833,"sku":"S0155-25MG","price":488.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s0155-pdm11-chemical-structure.gif?v=1776171915","url":"https:\/\/absource.de\/products\/pdm-11-s0155","provider":"Absource Diagnostics","version":"1.0","type":"link"}