{"product_id":"pemetrexed-disodium-heptahydrate-e4818","title":"Pemetrexed (disodium heptahydrate)","description":"\u003cp\u003e\u003cstrong\u003ePemetrexed (disodium heptahydrate)\u003c\/strong\u003e is an inhibitor linked to MAPK \/ ERK Signaling and DNA Damage Response and related signaling programs and related pathway-oriented research. It is especially relevant in apoptosis, cancer, and dna damage \/ repair models, where defined compound exposure can be linked to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and checkpoint activation, DNA repair, and genome-stability control.\u003c\/p\u003e\n\n\u003cp\u003eThe pathway annotation connects Pemetrexed (disodium heptahydrate) to MAPK \/ ERK Signaling and DNA Damage Response and related signaling programs, supporting experiments that monitor mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and checkpoint activation, DNA repair, and genome-stability control across biochemical, cellular, or phenotypic assay formats. This context is compatible with phosphorylation mapping, pathway-response, and growth assays and DNA-repair, checkpoint, and genotoxic-stress assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis, cancer, and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003ePathway perturbation studies connected to MAPK \/ ERK Signaling and DNA Damage Response and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in apoptosis, cancer, and dna damage \/ repair models\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Pemetrexed (disodium heptahydrate) is well suited to pathway-oriented studies that need a defined compound input for MAPK \/ ERK Signaling and DNA Damage Response and related signaling programs readouts in apoptosis, cancer, and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"50 mg","offer_id":57804964692313,"sku":"E4818-50MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"250 mg","offer_id":57804964725081,"sku":"E4818-250MG","price":363.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E4818-Pemetrexed-disodium-heptahydrate-chemical-structure.png?v=1776170133","url":"https:\/\/absource.de\/products\/pemetrexed-disodium-heptahydrate-e4818","provider":"Absource Diagnostics","version":"1.0","type":"link"}