{"product_id":"phtpp-s8686","title":"PHTPP","description":"\u003cp\u003e\u003cstrong\u003ePHTPP\u003c\/strong\u003e is an antagonist of Estrogen\/Progesterone Receptors used in studies of Hormone Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ligand-dependent transcriptional programs and endocrine regulation in endocrinology models.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking Estrogen\/Progesterone Receptors, PHTPP can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Estrogen\/Progesterone Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Hormone Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, PHTPP is appropriate when a defined chemical perturbant is needed to connect Estrogen\/Progesterone Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57809634689369,"sku":"S8686-10MG","price":124.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809634722137,"sku":"S8686-25MG","price":311.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809634754905,"sku":"S8686-1ML\/DMSO","price":134.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/phtpp-chemical-structure-s8686.gif?v=1776204489","url":"https:\/\/absource.de\/products\/phtpp-s8686","provider":"Absource Diagnostics","version":"1.0","type":"link"}