{"product_id":"pik3ca-h1047r-antibody-ffpe-validated","title":"PIK3CA-H1047R Antibody - FFPE Validated","description":"\u003ch2\u003eProtein Function\u003c\/h2\u003e\n\u003cp\u003eThis antibody enables you to examine PIK3CA-H1047R with a direct, biology-first readout. PIK3CA-H1047R is a pathway component whose activation state and localization can change after stimulation. Look for shifts in distribution that track with phenotype changes.\u003c\/p\u003e\n\u003cp\u003eMonitoring PIK3CA-H1047R alongside context markers can improve interpretation when phenotypes are subtle.\u003c\/p\u003e\n\u003ch2\u003eExperimental Applications\u003c\/h2\u003e\n\u003cp\u003eSignaling targets are typically assessed across time courses to capture transient activation windows. Pair measurements with orthogonal readouts when interpretation is sensitive to context.\u003c\/p\u003e\n\u003cp\u003eMany workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies. In oncology research models, expression shifts can accompany changes in adhesion, signaling, or differentiation state.\u003c\/p\u003e\n\u003cp\u003eCommon experimental questions that benefit from target tracking include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003etime-resolved changes following stimulation or inhibition\u003c\/li\u003e\n\u003cli\u003elocalization shifts between cytoplasm, membrane, and nucleus\u003c\/li\u003e\n\u003cli\u003einteraction patterns within multi-protein complexes\u003c\/li\u003e\n\u003cli\u003econdition-to-condition comparisons with matched controls\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWorkflow Perspective\u003c\/h2\u003e\n\u003cp\u003eBecause fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.\u003c\/p\u003e\n\u003cp\u003eTo support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so PIK3CA-H1047R patterns can be compared across experiments without guesswork.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting PIK3CA-H1047R, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eWith a clear focus on PIK3CA-H1047R, this fixed-section option fits streamlined studies and fast iteration.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101489729881,"sku":"52731M-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101489762649,"sku":"52731M-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101489795417,"sku":"52731M-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101489828185,"sku":"52731M-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101489860953,"sku":"52731M-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101489893721,"sku":"52731M-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/pi3k-mutation-antibody_81f01b0d-f7fc-46c8-b8b3-0dd5966da421.jpg?v=1779280042","url":"https:\/\/absource.de\/products\/pik3ca-h1047r-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}