{"product_id":"plakoglobin-gamma-catenin-or-jup-antibody-western-blot-validated","title":"Plakoglobin (gamma-catenin or JUP) Antibody - Western Blot Validated","description":"\u003ch2\u003eScientific Overview\u003c\/h2\u003e\n\u003cp\u003eBring Plakoglobin into view to evaluate changes across conditions. Plakoglobin is a contact-site protein that shapes barrier properties and signaling at the cell surface. Look for shifts in distribution that track with phenotype changes.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol JUP.\u003c\/p\u003e\n\u003ch2\u003eResearch Relevance\u003c\/h2\u003e\n\u003cp\u003eIn cultured models, junctional readouts can change rapidly after calcium modulation or cytoskeletal perturbation. Pair measurements with orthogonal readouts when interpretation is sensitive to context.\u003c\/p\u003e\n\u003cp\u003eBecause cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.\u003c\/p\u003e\n\u003cp\u003eWhen building a narrative around the target, it helps to track:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003cli\u003eco-localization patterns with cytoskeletal elements\u003c\/li\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplication-Specific Context\u003c\/h2\u003e\n\u003cp\u003eWhen samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting Plakoglobin, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eIf your study spans multiple model systems, it can help to define a shared reference condition for Plakoglobin so cross-sample contrasts stay meaningful.\u003c\/p\u003e\n\u003cp\u003eWith a clear focus on Plakoglobin, this denaturing-format option fits streamlined studies and fast iteration.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102395699545,"sku":"00191-WB-50UL","price":530.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102395732313,"sku":"00191-WB-50UL+1UG","price":599.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102395765081,"sku":"00191-WB-50UL+10UG","price":649.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102395797849,"sku":"00191-WB-200UL","price":1130.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102395830617,"sku":"00191-WB-200UL+1UG","price":1199.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102395863385,"sku":"00191-WB-200UL+10UG","price":1249.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/pg-skin-e15.jpg?v=1779283341","url":"https:\/\/absource.de\/products\/plakoglobin-gamma-catenin-or-jup-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}