{"product_id":"plakophilin-2-pkp2-antibody-ffpe-validated","title":"Plakophilin-2 (PKP2) Antibody - FFPE Validated","description":"\u003ch2\u003eScientific Overview\u003c\/h2\u003e\n\u003cp\u003eWhen control selection matters, this antibody helps you examine Plakophilin-2 (PKP2) in a structured study. Plakophilin-2 is a structural regulator of intercellular boundaries and tissue architecture. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.\u003c\/p\u003e\n\u003cp\u003eMonitoring Plakophilin-2 alongside context markers can improve interpretation when phenotypes are subtle.\u003c\/p\u003e\n\u003ch2\u003eResearch Relevance\u003c\/h2\u003e\n\u003cp\u003eShifts in junction organization can accompany migration, tissue morphogenesis, and altered mechanical tension. Time course design can be decisive when regulation is transient or compartment dependent.\u003c\/p\u003e\n\u003cp\u003eSince many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.\u003c\/p\u003e\n\u003cp\u003eWhen building a narrative around the target, it helps to track:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003cli\u003eco-localization patterns with cytoskeletal elements\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplication-Specific Context\u003c\/h2\u003e\n\u003cp\u003eBecause fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. Align controls to the expected direction of change to support confident interpretation.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting Plakophilin-2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eThe fixed-section format fits designs where Plakophilin-2 (PKP2) is evaluated with deliberate controls and careful comparisons.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102392881497,"sku":"00194-FFPE-50UL","price":530.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102392914265,"sku":"00194-FFPE-50UL+1UG","price":599.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102392947033,"sku":"00194-FFPE-50UL+10UG","price":649.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102392979801,"sku":"00194-FFPE-200UL","price":1130.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102393012569,"sku":"00194-FFPE-200UL+1UG","price":1199.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102393045337,"sku":"00194-FFPE-200UL+10UG","price":1249.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/pkp2-skin-e15_84381955-b405-4c5a-9557-f0f073236bee.jpg?v=1779283329","url":"https:\/\/absource.de\/products\/plakophilin-2-pkp2-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}