{"product_id":"plce1-plce-antibody-western-blot-validated","title":"PLCE1 (PLCE) Antibody - Western Blot Validated","description":"\u003ch2\u003eScientific Overview\u003c\/h2\u003e\n\u003cp\u003eThis antibody helps you assess PLCE1 while keeping condition-to-condition contrasts straightforward. PLCE1 is a membrane-associated component that helps organize cell-cell contacts and polarity. Use matched handling so differences reflect biology rather than processing.\u003c\/p\u003e\n\u003cp\u003eTracking PLCE1 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.\u003c\/p\u003e\n\u003ch2\u003eResearch Relevance\u003c\/h2\u003e\n\u003cp\u003eIn cultured models, junctional readouts can change rapidly after calcium modulation or cytoskeletal perturbation. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.\u003c\/p\u003e\n\u003cp\u003eBecause cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling. Kidney disease modeling efforts may include this target when exploring podocyte stress responses and structural change.\u003c\/p\u003e\n\u003cp\u003eWhen building a narrative around the target, it helps to track:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003cli\u003eco-localization patterns with cytoskeletal elements\u003c\/li\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplication-Specific Context\u003c\/h2\u003e\n\u003cp\u003eIf your primary readout depends on denatured protein presentation, this option can streamline comparison across lanes and conditions. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. A short pilot series can help set exposure ranges and reduce reruns.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing PLCE1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eFor multi-run studies, the denaturing-format option helps keep PLCE1 trends comparable from experiment to experiment.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102420078937,"sku":"00183-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102420111705,"sku":"00183-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102420144473,"sku":"00183-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102420177241,"sku":"00183-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102420210009,"sku":"00183-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102420242777,"sku":"00183-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/plce1-kid-pfa.jpg?v=1779283383","url":"https:\/\/absource.de\/products\/plce1-plce-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}