{"product_id":"plk4-sak-or-stk18-antibody-ffpe-validated","title":"PLK4 (SAK or STK18) Antibody - FFPE Validated","description":"\u003ch2\u003eProtein Function\u003c\/h2\u003e\n\u003cp\u003eUse this antibody to assess PLK4 when mapping complex behavior and signaling context. PLK4 is a regulator within kinase-driven cascades that influence transcriptional and metabolic responses. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol SAK.\u003c\/p\u003e\n\u003ch2\u003eExperimental Applications\u003c\/h2\u003e\n\u003cp\u003eSignaling targets are typically assessed across time courses to capture transient activation windows. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.\u003c\/p\u003e\n\u003cp\u003eTarget-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing.\u003c\/p\u003e\n\u003cp\u003eCommon experimental questions that benefit from target tracking include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003einteraction patterns within multi-protein complexes\u003c\/li\u003e\n\u003cli\u003elocalization shifts between cytoplasm, membrane, and nucleus\u003c\/li\u003e\n\u003cli\u003etime-resolved changes following stimulation or inhibition\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWorkflow Perspective\u003c\/h2\u003e\n\u003cp\u003eBecause fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. If interactions are a focus, consider parallel readouts for key partners.\u003c\/p\u003e\n\u003cp\u003eTo support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so PLK4 patterns can be compared across experiments without guesswork.\u003c\/p\u003e\n\u003cp\u003eTo support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so PLK4 patterns can be compared across experiments without guesswork.\u003c\/p\u003e\n\u003cp\u003eUse the fixed-section version to relate PLK4 behavior to upstream cues and downstream consequences.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101611594073,"sku":"50964-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101611626841,"sku":"50964-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101611659609,"sku":"50964-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101611692377,"sku":"50964-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101611725145,"sku":"50964-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101611757913,"sku":"50964-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/plk4-retina-pfa-0.5-5min_e0795b1c-5ec1-4afb-afa3-f91fce984cbc.jpg?v=1779280677","url":"https:\/\/absource.de\/products\/plk4-sak-or-stk18-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}