{"product_id":"plk4-sak-or-stk18-antibody","title":"PLK4 (SAK or STK18) Antibody","description":"\u003ch2\u003eScientific Overview\u003c\/h2\u003e\n\u003cp\u003eThis antibody is suited for researchers who want to explore PLK4 (SAK) and relate it to cell-state biology. PLK4 is a pathway component whose activation state and localization can change after stimulation. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol SAK.\u003c\/p\u003e\n\u003ch2\u003eResearch Relevance\u003c\/h2\u003e\n\u003cp\u003eParallel measurement of upstream inputs and downstream readouts can sharpen interpretation of pathway behavior. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.\u003c\/p\u003e\n\u003cp\u003eWhen cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.\u003c\/p\u003e\n\u003cp\u003eWhen building a narrative around the target, it helps to track:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003econdition-to-condition comparisons with matched controls\u003c\/li\u003e\n\u003cli\u003elocalization shifts between cytoplasm, membrane, and nucleus\u003c\/li\u003e\n\u003cli\u003einteraction patterns within multi-protein complexes\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplication-Specific Context\u003c\/h2\u003e\n\u003cp\u003eWhen assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed.\u003c\/p\u003e\n\u003cp\u003eTo support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so PLK4 patterns can be compared across experiments without guesswork.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing PLK4 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eThe regular format version supports deeper biological narratives around PLK4 (SAK) without overcomplicating setup.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101611856217,"sku":"50964-50UL","price":305.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101611888985,"sku":"50964-50UL+1UG","price":374.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101611921753,"sku":"50964-50UL+10UG","price":424.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101611954521,"sku":"50964-200UL","price":635.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101611987289,"sku":"50964-200UL+1UG","price":704.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101612020057,"sku":"50964-200UL+10UG","price":754.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/plk4-retina-pfa-0.5-5min_f03db29c-a7c5-4ac4-b7f7-94d52a71b769.jpg?v=1779280678","url":"https:\/\/absource.de\/products\/plk4-sak-or-stk18-antibody","provider":"Absource Diagnostics","version":"1.0","type":"link"}