{"product_id":"plus-dizocilpine-mk-801-maleate-s2876","title":"(+)-Dizocilpine (MK 801)Maleate","description":"\u003cp\u003e\u003cstrong\u003e(+)-Dizocilpine (MK 801)Maleate\u003c\/strong\u003e is an antagonist of NMDAR used in studies of Calcium Signaling. In practice, this places the compound in experiments that measure calcium flux, excitability, and secretion-linked signaling in neuroscience models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking NMDAR, (+)-Dizocilpine (MK 801)Maleate can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving NMDAR\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Calcium Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eElectrophysiology, ion-flux, and membrane-potential studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, (+)-Dizocilpine (MK 801)Maleate is appropriate when a defined chemical perturbant is needed to connect NMDAR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57805797130585,"sku":"S2876-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805797163353,"sku":"S2876-1G","price":1641.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/mk-801-maleate-chemical-structure-s2876.gif?v=1776175877","url":"https:\/\/absource.de\/products\/plus-dizocilpine-mk-801-maleate-s2876","provider":"Absource Diagnostics","version":"1.0","type":"link"}