{"product_id":"pomalidomide-cc-4047-s1567","title":"Pomalidomide (CC-4047)","description":"\u003cp\u003e\u003cstrong\u003ePomalidomide (CC-4047)\u003c\/strong\u003e is a modulator of E3 Ligase used in studies of NF-kB Signaling and Immune Signaling and related signaling programs. In practice, this places the compound in experiments that measure inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in apoptosis, cancer, and cell cycle models.\u003c\/p\u003e\n\n\u003cp\u003eBy modulating E3 Ligase, Pomalidomide (CC-4047) can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving E3 Ligase\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to NF-kB Signaling and Immune Signaling and related signaling programs\u003c\/li\u003e\n\u003cli\u003eContext-dependent response profiling and mechanism comparison\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Pomalidomide (CC-4047) is appropriate when a defined chemical perturbant is needed to connect E3 Ligase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"50 mg","offer_id":57805312360793,"sku":"S1567-50MG","price":186.0,"currency_code":"EUR","in_stock":true},{"title":"200 mg","offer_id":57805312393561,"sku":"S1567-200MG","price":363.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805312426329,"sku":"S1567-1G","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805312459097,"sku":"S1567-1ML\/DMSO","price":265.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Pomalidomide-chemical-structure-S1567.gif?v=1776173740","url":"https:\/\/absource.de\/products\/pomalidomide-cc-4047-s1567","provider":"Absource Diagnostics","version":"1.0","type":"link"}