{"product_id":"ppp2ca-ppp2cb-antibody-sc-f3812","title":"PP2A C subunit Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003ePP2A C subunit is a target of interest in many antibody-based workflows. The Protein Phosphatase 2A (PP2A) C subunit serves as the catalytic core of the PP2A holoenzyme, a key serine\/threonine phosphatase involved in regulating vital cellular processes such as the cell cycle, growth, differentiation, apoptosis, and signal transduction. PP2A consists of a core dimer: the scaffolding A subunit, which has 15 HEAT repeats forming a flexible horseshoe shape, and the enzymatically active C subunit (~36 kDa). Depending on the literature source, PP2A C subunit may also be discussed as PP2A C subunit and Replication protein C.\u003c\/p\u003e\u003cp\u003eReported cellular context includes centromere, chromosome, cytoplasm, and cytoskeleton, which can matter when signal is compared across treatments or changing cell states. Following PP2A C subunit across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003ePP2A C subunit is commonly interpreted in the context of cancer, cell cycle, and cell signaling research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans centromere, chromosome, and cytoplasm, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between centromere, chromosome, and cytoplasm across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003ecell-cycle linked differences in abundance, timing, or compartmental enrichment\u003c\/li\u003e\n\u003cli\u003esignal-dependent shifts after ligand, inhibitor, or growth-factor perturbation\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for PP2A C subunit. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in PP2A C subunit reflect biology rather than handling. When interpreting PP2A C subunit, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep PP2A C subunit trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57578048782681,"sku":"F3812-20UL","price":139.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57578048815449,"sku":"F3812-100UL","price":329.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57578048848217,"sku":"F3812-2X100UL","price":489.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F3812-IF.png?v=1773601502","url":"https:\/\/absource.de\/products\/ppp2ca-ppp2cb-antibody-sc-f3812","provider":"Absource Diagnostics","version":"1.0","type":"link"}