{"product_id":"prlr-antibody-sc-f2038","title":"Prolactin Receptor\/PRL-R Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eThe prolactin receptor (PRLR) is a membrane-bound glycoprotein and a member of the class I cytokine receptor family, encoded by the PRLR gene located on chromosome 5. It is expressed as multiple isoforms, long, short, and intermediate, that arise through alternative promoter usage and mRNA splicing. Depending on the literature source, PRLR may also be discussed as Prolactin Receptor\/PRL-R and Prolactin receptor.\u003c\/p\u003e\u003cp\u003eReported cellular context includes membrane and secreted, which can matter when signal is compared across treatments or changing cell states. Following PRLR across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003ePRLR is commonly interpreted in the context of immunology, metabolism, and cell signaling research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans membrane and secreted, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between membrane and secreted across matched conditions\u003c\/li\u003e\n\u003cli\u003econtext differences tied to immune-cell state, activation, or lineage composition\u003c\/li\u003e\n\u003cli\u003eresponses linked to nutrient status, mitochondrial state, or metabolic rewiring\u003c\/li\u003e\n\u003cli\u003esignal-dependent shifts after ligand, inhibitor, or growth-factor perturbation\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for PRLR. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in PRLR reflect biology rather than handling. When interpreting PRLR, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep PRLR trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577848897881,"sku":"F2038-20UL","price":169.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577848930649,"sku":"F2038-100UL","price":419.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577848963417,"sku":"F2038-2X100UL","price":629.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2038-IF.png?v=1773600130","url":"https:\/\/absource.de\/products\/prlr-antibody-sc-f2038","provider":"Absource Diagnostics","version":"1.0","type":"link"}