{"product_id":"prox1-antibody-sc-f2796","title":"PROX1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eProspero homeobox protein 1 (PROX1) is a transcription factor essential for organ development and lymphangiogenesis. It is crucial for the formation of the central nervous system (CNS), lens, retina, liver, pancreas, and heart, and is recognized as the master regulator of the lymphatic system. PROX1 drives the differentiation of lymphatic vasculature from the cardinal vein, a process regulated by Sox18. Depending on the literature source, PROX1 may also be discussed as Prox 1.\u003c\/p\u003e\u003cp\u003eReported cellular context includes nucleus, which can matter when signal is compared across treatments or changing cell states. Following PROX1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003ePROX1 is commonly interpreted in the context of cancer, cardiovascular, and developmental biology research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans nucleus, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003esignal enrichment within nucleus relative to the broader cellular background\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003echanges linked to vascular, contractile, or hemodynamic cell-state cues\u003c\/li\u003e\n\u003cli\u003estage-dependent patterns during differentiation, morphogenesis, or lineage commitment\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for PROX1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in PROX1 reflect biology rather than handling. When interpreting PROX1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep PROX1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577972597081,"sku":"F2796-20UL","price":159.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577972629849,"sku":"F2796-100UL","price":339.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577972662617,"sku":"F2796-2X100UL","price":499.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2796-IF.png?v=1773600700","url":"https:\/\/absource.de\/products\/prox1-antibody-sc-f2796","provider":"Absource Diagnostics","version":"1.0","type":"link"}