{"product_id":"ra-190-s6851","title":"RA-190","description":"\u003cp\u003e\u003cstrong\u003eRA-190\u003c\/strong\u003e is an inhibitor of Proteasome and E3 Ligase used in studies of Apoptosis and Autophagy and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to caspase-associated cell-death signaling and survival decisions and autophagic flux, lysosomal turnover, and stress adaptation in autophagy, cancer, and protein homeostasis models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Proteasome and E3 Ligase, RA-190 can be used to examine caspase-associated cell-death signaling and survival decisions and autophagic flux, lysosomal turnover, and stress adaptation. The protease annotation adds relevance to protease-activity, cleavage, and substrate-processing assays, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and protein homeostasis models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Proteasome and E3 Ligase\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Apoptosis and Autophagy and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eProtease-activity, cleavage, and substrate-processing assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, RA-190 is appropriate when a defined chemical perturbant is needed to connect Proteasome and E3 Ligase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and protein homeostasis models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 5 mg","offer_id":57809431986521,"sku":"S6851-5MG","price":173.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 25 mg","offer_id":57809432019289,"sku":"S6851-25MG","price":527.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 5 mg","offer_id":58478825046361,"sku":"C12270-5MG","price":129.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 25 mg","offer_id":58478825079129,"sku":"C12270-25MG","price":393.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s6851-ra190-chemical-structure.gif?v=1776200590","url":"https:\/\/absource.de\/products\/ra-190-s6851","provider":"Absource Diagnostics","version":"1.0","type":"link"}