{"product_id":"rmc-4998-e1959","title":"RMC-4998","description":"\u003cp\u003e\u003cstrong\u003eRMC-4998\u003c\/strong\u003e is an inhibitor of KRAS used in studies of PI3K-Akt-mTOR Signaling and MAPK \/ ERK Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in cancer and cell signaling models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting KRAS, RMC-4998 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. This context is compatible with AKT\/mTOR readouts, pathway-response, and viability assays and phosphorylation mapping, pathway-response, and growth assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving KRAS\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and MAPK \/ ERK Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cancer and cell signaling models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, RMC-4998 is appropriate when a defined chemical perturbant is needed to connect KRAS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"1 mg","offer_id":57804547621209,"sku":"E1959-1MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"5 mg","offer_id":57804547653977,"sku":"E1959-5MG","price":341.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804547686745,"sku":"E1959-25MG","price":763.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804547719513,"sku":"E1959-100MG","price":1739.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E1959-RMC-4998-chemical-structure.png?v=1776167511","url":"https:\/\/absource.de\/products\/rmc-4998-e1959","provider":"Absource Diagnostics","version":"1.0","type":"link"}