{"product_id":"rrx-001-s8405","title":"RRx-001","description":"\u003cp\u003e\u003cstrong\u003eRRx-001\u003c\/strong\u003e is an inhibitor of Dehydrogenases and NRF2 used in studies of Apoptosis and Oxidative Stress Response and related signaling programs. In practice, this places the compound in experiments that measure caspase-associated cell-death signaling and survival decisions and redox signaling, ROS handling, and antioxidant defenses in apoptosis, cancer, and epigenetics models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Dehydrogenases and NRF2, RRx-001 can be used to examine caspase-associated cell-death signaling and survival decisions and redox signaling, ROS handling, and antioxidant defenses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Dehydrogenases and NRF2\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Apoptosis and Oxidative Stress Response and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, RRx-001 is appropriate when a defined chemical perturbant is needed to connect Dehydrogenases and NRF2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 5 mg","offer_id":57809608147289,"sku":"S8405-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 25 mg","offer_id":57809608180057,"sku":"S8405-25MG","price":488.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 1 ml (10mM\/DMSO)","offer_id":57809608212825,"sku":"S8405-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 5 mg","offer_id":58479027945817,"sku":"C13398-5MG","price":108.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 25 mg","offer_id":58479027978585,"sku":"C13398-25MG","price":365.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/rrx-001-chemical-structure-s8405.gif?v=1776202688","url":"https:\/\/absource.de\/products\/rrx-001-s8405","provider":"Absource Diagnostics","version":"1.0","type":"link"}