{"product_id":"saccharin-1-methylimidazole-smi-s8326","title":"Saccharin 1-methylimidazole (SMI)","description":"\u003cp\u003e\u003cstrong\u003eSaccharin 1-methylimidazole (SMI)\u003c\/strong\u003e is an activator of DNA\/RNA Synthesis used in studies of DNA Damage Response. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control in cancer and dna damage \/ repair models.\u003c\/p\u003e\n\n\u003cp\u003eBy activating DNA\/RNA Synthesis, Saccharin 1-methylimidazole (SMI) can be used to examine checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving DNA\/RNA Synthesis\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response\u003c\/li\u003e\n\u003cli\u003eGain-of-function pathway-activation studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Saccharin 1-methylimidazole (SMI) is appropriate when a defined chemical perturbant is needed to connect DNA\/RNA Synthesis with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57809601298777,"sku":"S8326-10MG","price":95.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/saccharin-1-methylimidazole-smi-chemical-structure-s8326.gif?v=1776202597","url":"https:\/\/absource.de\/products\/saccharin-1-methylimidazole-smi-s8326","provider":"Absource Diagnostics","version":"1.0","type":"link"}