{"product_id":"sc75741-s7273","title":"SC75741","description":"\u003cp\u003e\u003cstrong\u003eSC75741\u003c\/strong\u003e is an inhibitor of NF-kB used in studies of NF-kB Signaling and Immune Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in immunology and inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting NF-kB, SC75741 can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving NF-kB\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to NF-kB Signaling and Immune Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, SC75741 is appropriate when a defined chemical perturbant is needed to connect NF-kB with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57809468948825,"sku":"S7273-10MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57809468981593,"sku":"S7273-50MG","price":481.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809469014361,"sku":"S7273-1G","price":2938.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809469047129,"sku":"S7273-1ML\/DMSO","price":242.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/SC75741-chemical-structure-s7273.gif?v=1776201146","url":"https:\/\/absource.de\/products\/sc75741-s7273","provider":"Absource Diagnostics","version":"1.0","type":"link"}