{"product_id":"shank3-antibody-ffpe-validated","title":"SHANK3 Antibody - FFPE Validated","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\n\u003cp\u003eThis antibody is suited for researchers who want to explore SHANK3 and relate it to cell-state biology. SHANK3 is a receptor or synapse-associated protein that supports neuronal signaling and connectivity. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.\u003c\/p\u003e\n\u003cp\u003eMonitoring SHANK3 alongside context markers can improve interpretation when phenotypes are subtle.\u003c\/p\u003e\n\u003ch2\u003eResearch Context\u003c\/h2\u003e\n\u003cp\u003eIn mixed cultures, cell-type composition can influence apparent signal, so normalization strategies matter. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions. Neural differentiation and synaptic organization projects may include this target as a contextual readout.\u003c\/p\u003e\n\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eregional localization along neurites and synaptic compartments\u003c\/li\u003e\n\u003cli\u003eactivity-linked changes in abundance or distribution\u003c\/li\u003e\n\u003cli\u003einteraction tendencies with scaffold or receptor partners\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\n\u003cp\u003eBecause fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting SHANK3, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eTo support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so SHANK3 patterns can be compared across experiments without guesswork.\u003c\/p\u003e\n\u003cp\u003eThe fixed-section version supports deeper biological narratives around SHANK3 without overcomplicating setup.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101860041049,"sku":"15123-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101860073817,"sku":"15123-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101860106585,"sku":"15123-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101860139353,"sku":"15123-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101860172121,"sku":"15123-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101860204889,"sku":"15123-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/shak3aq4_4b89fd69-2a87-4a8a-a0fa-7b6ce613cc00.jpg?v=1779281911","url":"https:\/\/absource.de\/products\/shank3-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}