{"product_id":"slc7a5-lat1-antibody-sc-f3212","title":"SLC7A5\/LAT1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eSLC7A5\/LAT1 (Large Neutral Amino Acid Transporter 1), is a sodium- and pH-independent transmembrane transporter belonging to the SLC7 family within the APC superfamily. Structurally, it forms a heterodimeric complex with CD98 (SLC3A2) through a conserved disulfide bond, enabling the uptake of essential amino acids (e. g., leucine, phenylalanine) in exchange for intracellular amino acids like glutamine. Depending on the literature source, SLC7A5\/LAT1 may also be discussed as SLC7A5\/LAT1.\u003c\/p\u003e\u003cp\u003eReported cellular context includes apical cell membrane, cell membrane, and lysosome membrane, which can matter when signal is compared across treatments or changing cell states. Following SLC7A5\/LAT1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eSLC7A5\/LAT1 is commonly interpreted in the context of cancer, immunology, and metabolism research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans apical cell membrane, cell membrane, and lysosome membrane, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between apical cell membrane, cell membrane, and lysosome membrane across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003econtext differences tied to immune-cell state, activation, or lineage composition\u003c\/li\u003e\n\u003cli\u003eresponses linked to nutrient status, mitochondrial state, or metabolic rewiring\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for SLC7A5\/LAT1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in SLC7A5\/LAT1 reflect biology rather than handling. When interpreting SLC7A5\/LAT1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep SLC7A5\/LAT1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57578009035097,"sku":"F3212-20UL","price":95.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57578009067865,"sku":"F3212-100UL","price":289.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57578009100633,"sku":"F3212-2X100UL","price":459.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F3212-IF.png?v=1773601021","url":"https:\/\/absource.de\/products\/slc7a5-lat1-antibody-sc-f3212","provider":"Absource Diagnostics","version":"1.0","type":"link"}