{"product_id":"sm-7368-e0783","title":"SM-7368","description":"\u003cp\u003e\u003cstrong\u003eSM-7368\u003c\/strong\u003e is an inhibitor of NF-kB used in studies of MAPK \/ ERK Signaling and NF-kB Signaling and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and inflammatory transcriptional control and stress-responsive survival signaling in immunology and inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting NF-kB, SM-7368 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and inflammatory transcriptional control and stress-responsive survival signaling. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving NF-kB\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to MAPK \/ ERK Signaling and NF-kB Signaling and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, SM-7368 is appropriate when a defined chemical perturbant is needed to connect NF-kB with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804294914393,"sku":"E0783-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804294947161,"sku":"E0783-25MG","price":342.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e0783-sm-7368-chemical-structure.gif?v=1776166268","url":"https:\/\/absource.de\/products\/sm-7368-e0783","provider":"Absource Diagnostics","version":"1.0","type":"link"}