{"product_id":"smarca2-brm-antibody-sc-f2148","title":"SMARCA2 \/ BRM Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eSMARCA2 \/ BRM is a target of interest in many antibody-based workflows. SWI\/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily A member 2 (SMARCA2), also known as Brahma (BRM), is a key ATPase in the Snf2 family. BRM and its close relative, Brahma-related gene 1 (BRG1 or SMARCA4), are exclusive ATPases within the large ATP-dependent SWI\/SNF chromatin-remodeling complexes, which play a critical role in gene expression regulation. Depending on the literature source, SMARCA2 \/ BRM may also be discussed as SMARCA2 \/ BRM and BRM.\u003c\/p\u003e\u003cp\u003eReported cellular context includes nucleus, which can matter when signal is compared across treatments or changing cell states. Following SMARCA2 \/ BRM across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eSMARCA2 \/ BRM is commonly interpreted in the context of epigenetics research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans nucleus, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003esignal enrichment within nucleus relative to the broader cellular background\u003c\/li\u003e\n\u003cli\u003elinks between target behavior and transcriptional or chromatin-state changes\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003cli\u003etime-matched comparisons so changes reflect biology rather than handling or sampling drift\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for SMARCA2 \/ BRM. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in SMARCA2 \/ BRM reflect biology rather than handling. When interpreting SMARCA2 \/ BRM, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep SMARCA2 \/ BRM trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577872785753,"sku":"F2148-20UL","price":189.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577872818521,"sku":"F2148-100UL","price":429.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577872851289,"sku":"F2148-2X100UL","price":639.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2148-IHC1.jpg?v=1773600218","url":"https:\/\/absource.de\/products\/smarca2-brm-antibody-sc-f2148","provider":"Absource Diagnostics","version":"1.0","type":"link"}