{"product_id":"smoothened-smo-or-frizzled-11-or-fzd11-antibody-western-blot-validated","title":"Smoothened (SMO or Frizzled-11 or FZD11) Antibody - Western Blot Validated","description":"\u003ch2\u003eProtein Function\u003c\/h2\u003e\n\u003cp\u003eWhen you need to characterize Smoothened with attention to cellular organization, this antibody provides a focused option. Smoothened is a signaling node often evaluated by abundance, localization, and modification-dependent states. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.\u003c\/p\u003e\n\u003cp\u003eTracking Smoothened can clarify whether changes reflect regulation, redistribution, or altered complex assembly.\u003c\/p\u003e\n\u003ch2\u003eExperimental Applications\u003c\/h2\u003e\n\u003cp\u003ePerturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.\u003c\/p\u003e\n\u003cp\u003eTarget-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing. Planar polarity studies may connect this target to directional signaling and cytoskeletal alignment.\u003c\/p\u003e\n\u003cp\u003eCommon experimental questions that benefit from target tracking include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003etime-resolved changes following stimulation or inhibition\u003c\/li\u003e\n\u003cli\u003einteraction patterns within multi-protein complexes\u003c\/li\u003e\n\u003cli\u003econdition-to-condition comparisons with matched controls\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWorkflow Perspective\u003c\/h2\u003e\n\u003cp\u003eFor size-resolved readouts under denaturing conditions, this version helps you focus on expected band patterns and molecular weight regions. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.\u003c\/p\u003e\n\u003cp\u003eIf your study spans multiple model systems, it can help to define a shared reference condition for Smoothened so cross-sample contrasts stay meaningful.\u003c\/p\u003e\n\u003cp\u003eUse the denaturing-format variant when your project demands Smoothened readouts that respect preparation constraints.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101640593753,"sku":"50611-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101640626521,"sku":"50611-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101640659289,"sku":"50611-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101640692057,"sku":"50611-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101640724825,"sku":"50611-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101640757593,"sku":"50611-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/smo-retina-pfa-0.5-5min.jpg?v=1779280836","url":"https:\/\/absource.de\/products\/smoothened-smo-or-frizzled-11-or-fzd11-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}