{"product_id":"sofituzumab-vedotin","title":"Sofituzumab Vedotin","description":"\u003cp\u003e\u003cstrong\u003eSofituzumab Vedotin\u003c\/strong\u003e is an antibody-drug conjugate (ADC) that contains the humanized IgG1 anti-MUC16 monoclonal antibody (mAb) and a potent anti-mitotic agent, monomethyl auristatin E (MMAE), linked through a protease-labile linker.\u003c\/p\u003e\u003ch2\u003eProduct overview\u003c\/h2\u003e\u003cp\u003eDMUC5754A binds to the MUC16 extracellular domain with high affinity. The product background identifies the antibody component, target antigen and payload or linker architecture where these details are supplied. This ADC context supports comparison of antigen recognition, payload conjugation and cellular uptake behavior in controlled assay systems, especially when researchers need to distinguish conjugated biologics from unconjugated antibodies or standalone small molecules.\u003c\/p\u003e\u003ch2\u003eLaboratory context\u003c\/h2\u003e\u003cp\u003eThe listed workflow context supports binding and uptake-oriented laboratory studies where a defined antibody component, cellular target and conjugated payload are relevant to assay planning, including cell-surface binding, cell-uptake and protein-binding experiments, within oncology research.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Selleck \/ 1 mg","offer_id":58188061770073,"sku":"D4036-1MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"Selleck \/ 5 × 1 mg","offer_id":58188061802841,"sku":"D4036-5X1MG","price":2918.0,"currency_code":"EUR","in_stock":true},{"title":"Capsid \/ 1 mg","offer_id":58479154594137,"sku":"C00984-1MG","price":712.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/a2-serial-chemical-structure_c0541860-588a-40ea-8120-a8006cf5848f.gif?v=1780390087","url":"https:\/\/absource.de\/products\/sofituzumab-vedotin","provider":"Absource Diagnostics","version":"1.0","type":"link"}