{"product_id":"srsf1-antibody-sc-f2710","title":"SRSF1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eSerine\/Arginine Splicing Factor 1 (SRSF1) is a multifunctional RNA-binding protein and the founding member of the SR protein family, crucial for regulating mRNA metabolism, including splicing, stability, translation, nuclear export, and nonsense-mediated decay (NMD). Structurally, SRSF1 comprises two RNA recognition motifs (RRMs) at the N-terminus, with RRM2 playing a dominant role in substrate specificity, and a C-terminal RS domain involved in protein-protein interactions. Depending on the literature source, SRSF1 may also be discussed as SF2 and ASF.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cytoplasm, nucleus, and spliceosome, which can matter when signal is compared across treatments or changing cell states. Following SRSF1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state. In practice, this target is often considered at the family or isoform-group level, so experimental interpretation benefits from matched controls and clear comparison logic.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eSRSF1 is commonly interpreted in the context of cancer research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cytoplasm, nucleus, and spliceosome, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cytoplasm, nucleus, and spliceosome across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003cli\u003etime-matched comparisons so changes reflect biology rather than handling or sampling drift\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for SRSF1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in SRSF1 reflect biology rather than handling. When interpreting SRSF1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep SRSF1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577967812953,"sku":"F2710-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577967845721,"sku":"F2710-100UL","price":329.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577967878489,"sku":"F2710-2X100UL","price":489.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2710-IF.png?v=1773600639","url":"https:\/\/absource.de\/products\/srsf1-antibody-sc-f2710","provider":"Absource Diagnostics","version":"1.0","type":"link"}